The achievable resolution for X-ray imaging of cells and other soft biological material

Nave, C.

doi:10.1107/S2052252520002262

Figure 1
Values for required dose against resolution given in the literature, including this article. For details see Table 1

. The plots are for imaging protein against water/amorphous ice and based on theoretical calculations for CDI unless otherwise indicated. The CDI plots assume a 1/d⁴ resolution dependence of the required dose, except for the Villaneuva-Perez plot which assumes a W²/d⁶ dependence. The SCM plot assumes a W/d⁴ dependence. Note that the values of W for the experiments do not necessarily correspond to the simulations in Villaneuva-Perez et al. (2018

). Plots for the resolution dependence for the tolerable dose at which the intensity decreases by half are shown with a 100 MGy nm⁻¹ dependence (Howells et al., 2009