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Figure 7
Model of SigB regulation by RsbV and RsbW. (a) Model structure of the RsbW dimer in complex with SigB. The model was prepared by superimposing the RsbW dimer and the SigB homology model on the structure of the SpoIIAA–SigF complex. The RsbW dimer and SigB are drawn as a red ribbon diagram and a blue surface model, respectively. (b) Model structure of RsbW–SigB superimposed on the crystal structure of the RsbV–RsbW tetramer. In addition to (a), RsbV is drawn as a green ribbon model. In the model, SigB clashes with RsbV when they bind to RsbW, indicating that binding of RsbV and SigB to RsbW is mutually exclusive. (c) Model structure of the RsbW–SigB hexamer superimposed on the crystal structure of the RsbV–RsbW octamer. Surface-2 mediating dimerization of the RsbW dimer is shaded with yellow circles.

IUCrJ
Volume 7| Part 4| July 2020| Pages 737-747
ISSN: 2052-2525
https://doi.org/10.1107/S2052252520007617