Figure 1
(a) A selection of recently reported cryo-EM structures of SARS-CoV-2 proteins including spike proteins, RNA polymerase complexes and membrane proteins in the viral envelope. The PDB identifiers of the structures are indicated. (b) Negatively stained transmission electron microscopic image (Almeida & Tyrrell, 1967) of a novel virus that was named a `coronavirus' by June Almeida in 1966. (c) Colorized transmission electron microscope image of negatively stained infectious SARS-CoV-2 particles recorded at NIAID's Rocky Mountain Laboratories (RML) in Hamilton, Montana. The arrows in panels (b) and (c) point to the spike proteins on the surface of the virus particles. |