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Figure 5
The A and B conformations of Phe92 observed in our structure create pores with different diameters at the exit of the selectivity filter. The A conformation of Phe92 shown in magenta creates a pore with a diameter of 9.54 Å, which we refer to as the enlarged pore. The B conformation of Phe92 shown in blue creates a pore with a diameter of 6.55 Å, which we refer to as the restricted pore. We are defining the pore diameter as the shortest distance between atoms on opposing Phe92 residues in the ion channel based upon our crystal structure.

IUCrJ
Volume 7| Part 5| September 2020| Pages 835-843
ISSN: 2052-2525