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Figure 1
Summary of the reactions catalysed by the enzymes used in this study, i.e. the two 2OG-dependent oxygenases AlkB and VioC, and IPNS. The presence of a substrate in the active site is a clear indication of whether or not molecular dioxygen has diffused to the active site and reacted productively. The figure was constructed using the following structures: VioC:Fe:2OG:Arg (PDB entry 6y0n), VioC:Fe:SIN:(3S)-OH-Arg (PDB entry 6y12), AlkB:Fe:2OG:T-1-meA-T (PDB entry 6y0q), AlkB:Fe:2OG (PDB entry 6ypv) and IPNS:Fe:ACV (PDB entry 6y0o). SIN = succinate.

IUCrJ
Volume 7| Part 5| September 2020| Pages 901-912
ISSN: 2052-2525
https://doi.org/10.1107/S2052252520010374