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Figure 5
Ligand-induced conformational changes in the SARS-CoV-2 ADRP structure. (a) Superposition of the ADRP–ADPr complex (yellow; PDB entry 6w02, chain A) with ADRP–AMP (grey; PDB entry 6w6y, chain A), ADRP–MES (green; PDB entry 6wcf) and ADRP-APO2 (coral; PDB entry 6wen). The ligand molecules are shown in ball-and-stick representation. (b) As in (a), but rotated ∼90°. (c) Surface representation of the ADRP–ADPr complex. (d) Surface representation of the ADRP–MES complex. (e) Surface representation of the ADRP–AMP complex. (f) Surface representation of the ADRP-APO2 structure.

IUCrJ
Volume 7| Part 5| September 2020| Pages 814-824
ISSN: 2052-2525