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Figure 5
MX and adjoining helices in hydrophobicity surface representation (from PDB entry 6uwz; αδ subunit; tan, hydrophobic; purple, polar). MX and the link to M3 are held by hydrophobic contacts to the body of the receptor. Together they create an extensive hydrophobic `platform' facing the hydrophobic core of the bilayer and a polar side facing the zwitterionic phospholipid headgroups [the dashed lines correspond to their positions indicated in Fig. 2 (b)]. |
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