Figure 5
MX and adjoining helices in hydrophobicity surface representation (from PDB entry 6uwz; αδ subunit; tan, hydrophobic; purple, polar). MX and the link to M3 are held by hydrophobic contacts to the body of the receptor. Together they create an extensive hydrophobic `platform' facing the hydrophobic core of the bilayer and a polar side facing the zwitterionic phospholipid headgroups [the dashed lines correspond to their positions indicated in Fig. 2(b)]. |