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Figure 1
Use of contrast-matched LCP in SANS. The cartoon depicts conditions under which the lipid (a) is not contrast-matched and (b) is contrast-matched. Contrast-matching eliminates most of the scattering from the LCP, allowing any structures formed by non-deuterated components of the system to be observed by SANS. These could potentially include membrane protein (MP) molecules, protein/detergent complexes (PDCs) or detergent micelles/aggregates. Detergent monomers are not detectable due to their small size.

IUCrJ
Volume 8| Part 1| January 2021| Pages 22-32
ISSN: 2052-2525
https://doi.org/10.1107/S2052252520013974