view article
Figure 3
Crystal structures of D. melanogaster Dhd and TrxT. (a) Cartoon representation of the crystal structures of Dhd (left) and TrxT (right), showing the oxidized forms. Cys31/Cys32 and Cys34/35 in the catalytic motif are labeled. Secondary-structure elements are also indicated. For TrxT, part of the C-­terminal domain was connected to the Trx core domain by a disulfide bridge between Cys93 and Cys125. (b) Electron-density map of the Dhd active center including the pair of cysteines Cys31 and Cys34. Left: reduced chain B. Right: partially oxidized chain D. Top: 2Fo − Fc electron-density map contoured at 2.0σ. Bottom: 2Fo − Fc electron-density map contoured at 1.0σ. (c) The 2Fo − Fc electron-density map for the bound C-terminal fragment contoured at 1.0σ.

IUCrJ
Volume 8| Part 2| March 2021| Pages 281-294
ISSN: 2052-2525
https://doi.org/10.1107/S2052252521000221