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Figure 1
Classification of problems noted in various macromolecular structures. These problems, which are not an exhaustive list, may be difficult or even impossible to correct. Some criteria are case- and resolution-dependent, such as NCS and TLS (indicated in a different color). For example, the use of NCS may be critical for low-resolution structures due to the decreased number of parameters. Nonstandardized cell placement should be avoided because it makes it more difficult to compare two or more similar structures (also indicated by color). The classification may depend on who is looking at the structure, i.e. a crystallographer or a biologist.

IUCrJ
Volume 8| Part 3| May 2021| Pages 395-407
ISSN: 2052-2525
https://doi.org/10.1107/S2052252521003018