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Figure 5
(a) Structural comparison of the occluded, open and complex structures. Structural differences were observed in the LαA–β1 (red) and Lβ4–αD (green) loops. (b) Sequence alignment of the deaminase domains of AoRib2, ScRib2, Candida albicans Rib2 (CaRib2) and BsRibG. The substrate-binding residues in AoRib2 and BsRibG are shown in red and cyan, respectively; those predicted in ScRib2 and CaRib2 are shown in blue. |
ISSN: 2052-2525
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