Figure 9
Details of L-Asp (orange) binding in Class 2 asparaginases. (a) L-Asp bound in the active site of immature HsAIII (PDB entry 4pvr); a fragment of the linker region is shown in dark pink. (b) L-Asp in the active site of mature ECAIII and the residues stabilizing its binding (PDB entry 2zal). |