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Figure 1
Schematic representation of the results reported by Asthana et al. (2021BB1) within the context of cholesterol import through the M. tuberculosis cell envelope. Mce4A is shown to be monomeric in solution, likely forming a hetero-hexameric arrangement with other Mce4 proteins to form a tunnel for lipid transport. A schematic model of the M. tuberculosis cell envelope is also shown for comparison, adapted from Chiaradia et al. (2017BB4). The schematics are not drawn to scale.

IUCrJ
Volume 8| Part 5| September 2021| Pages 711-712
ISSN: 2052-2525
https://doi.org/10.1107/S2052252521008885