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Figure 2
MMQX experiments show evidence for the diffusion of OAA into the PEPCK active site and formation of the PEP product. FoFo analysis of 40 ms (cyan model) − unmixed (gray model) PEPCK data. FoFo maps shown at ±3.5 r.m.s.d. (blue, orange). (a) Overview of the asymmetric unit demonstrating that large difference-map peaks are concentrated in the active site. (b) View of the active site, showing difference-map peaks for PEP and relaxation of GDP.

Volume 8| Part 5| September 2021| Pages 784-792
ISSN: 2052-2525