Approximating deformation fields for the analysis of continuous heterogeneity of biological macromolecules by 3D Zernike polynomials

Herreros, D.; Lederman, R.R.; Krieger, J.; Jiménez-Moreno, A.; Martínez, M.; Myška, D.; Strelak, D.; Filipovic, J.; Bahar, I.; Carazo, J.M.; Sanchez, C.O.S.

doi:10.1107/S2052252521008903

Figure 1
Structure mapping recovered a set of seven maps of the human mitochondrial ribosomes (Amunts et al., 2015

) from the data set retrieved from the EMDB after running the Zernike3D algorithm. Two trajectories are suggested that might correspond to two independent states (pre-translocation and post-translocation) present in the data set, consistent with results from a previous normal-mode-based structure mapping algorithm (Sanchez Sorzano et al., 2016