Increase in the diffracted intensity per unit absorbed dose, 〈I〉/D, as a function of energy. Data shown are averaged from 29 data series (22 recorded using the CdTe EIGER and seven using the Si PILATUS), with the standard deviation at each energy shown as error bars. The variation in 〈I〉/D over an energy range of 22.3–27 keV observed in an additional five data series is shown in the inset. The data shown in the inset are normalized to 22.3 keV. The mean diffracted intensity, 〈I〉, is scaled to the illuminated crystal volume defined by the measured beam sizes given in Supplementary Table S2.