Using crystallography tools to improve vaccine formulations

Fantini, M.C.A.; Oliveira, C.L.P.; Lopes, J.L.S.; Martins, T.S.; Akamatsu, M.A.; Trezena, A.G.; Franco, M.T.-D.-; Botosso, V.F.; Sant'Anna, O.A.B.E.; Kardjilov, N.; Rasmussen, M.K.; Bordallo, H.N.

doi:10.1107/S205225252101071X

Figure 10
Anti-diphtheria serum IgG titers detected by ELISA in BALB/c mice immunized with dANA encapsulated/adsorbed in mesoporous SBA-15 or adsorbed in Al(OH)₃ by subcutaneous (SC) or oral (OR) routes. The titers were detected 7 (grey columns) and 19 (black columns) days after immunization. The statistical analyses were performed with the one-way ANOVA test (*P < 0.05; ***P < 0.005) [reproduced from the work by Rasmussen et al. (2021