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Figure 9
Anti-HBsAg serum IgG and subclass titers detected by ELISA in BALB/c mice immunized with HBsAg, encapsulated/adsorbed in mesoporous SBA-15 or adsorbed in Al(OH)3 by subcutaneous (SC) or oral (OR) routes. The titers were detected 7, 14 and 30 days after the booster. A group of animals immunized with rHBsAg was used as a reference for the unpaired Student t test analysis, *p < 0.05; ⋯ p < 0.001. Antibody titers at days 7, 14 and 30 after the booster were also used as a reference for the unpaired Student t test analysis, °p < 0.05 [reproduced from the work by Scaramuzzi et al., 2011BB27)].

IUCrJ
Volume 9| Part 1| January 2022| Pages 11-20
ISSN: 2052-2525
https://doi.org/10.1107/S205225252101071X