Consecutive steps of crystal structure determination and sequence identification of a protein with hemolytic activity purified from B. atrox venom. (a) Initial MR solution after 30 REFMAC5 refinement cycles with jelly-body restraints. The same fragment in (b) the ARP/wARP model re-traced without an input sequence and used as an input for findMySequence, and in (c) the final model. The 2Fo − Fc maps are contoured at the 1σ level above the mean. The free atoms used for sparse electron-density map representation in ARP/wARP are shown as grey spheres. Water molecules are shown as red spheres.