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Figure 2
Differences between X-ray and electron diffraction. Diffraction patterns are shown for X-ray diffraction and MicroED. The much shorter wavelength of high-energy electrons means that the Ewald sphere construction is virtually flat. Indexing from a single diffraction frame is therefore not typically possible for electron diffraction, and a larger wedge of reciprocal space needs to be covered to find the unit-cell dimensions.

IUCrJ
Volume 9| Part 2| March 2022| Pages 169-179
ISSN: 2052-2525
https://doi.org/10.1107/S2052252521013063