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Figure 4
MicroED for small-molecule research. (a) Typical workflow involved for MicroED of small-molecule samples from powder to individual crystals on a standard EM grid, data collection, processing and structure solution. The solved structure in the last panel shows the model of the compound limaspermidine with the observed map showing the individual atoms (blue, top), and the difference map showing hydrogen atom positions (green, bottom). (b) Individual compounds can be identified from heterogeneous mixtures using MicroED. Resolution rings are shown at 0.8 Å (blue).

IUCrJ
Volume 9| Part 2| March 2022| Pages 169-179
ISSN: 2052-2525
https://doi.org/10.1107/S2052252521013063