view article
Figure 2
The I923.40N mutant structure of A2AAR in complex with UK-432097. (a) The overall structure with agonist UK-432097 shown as yellow sticks and Asn923.40 shown as spheres. (b) A zoomed-in view of the region around Asn923.40 within the mutant structure. Hydrophilic interactions are marked with red dashed lines. (c) A superposition of the mutant structure with the intermediate-state WT structure (PDB ID 3qak). The electronic densities between Asn92 and Trp246 are shown at 2Fo − Fc of 1.0σ. In the WT structure the carbons are shown as light orange.

IUCrJ
Volume 9| Part 3| May 2022| Pages 333-341
ISSN: 2052-2525
https://doi.org/10.1107/S2052252522001907