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Figure 2
(a) Ribbon plot of the overall joint XN structure of the NBD of Hsp72 in complex with ADP (PDB entry 7f4x). Subdomains IA, IB, IIA and IIB are coloured cyan, split pea, green and light blue, respectively. The ADP molecule and the side chains of Thr204 and Tyr149 are shown as stick models. Water clusters 1, 2 and 3 are shown as stick and semi-transparent surface models in grey, magenta and orange, respectively. (b) Top: the |Fo| − |Fc| neutron scattering length density map omitting ADP contoured at +4σ. Bottom: the |Fo| − |Fc| electron-density map omitting ADP contoured at +4σ (blue) and the |Fo| − |Fc| neutron scattering length density map omitting H and D atoms contoured at +3.3σ (green) and −3.3σ (red). (c) The H/D-exchanged and unexchanged regions are projected in the ribbon model. The H/D-exchanged and unexchanged regions are coloured blue and red, respectively.

IUCrJ
Volume 9| Part 5| September 2022| Pages 562-572
ISSN: 2052-2525
https://doi.org/10.1107/S2052252522006297