Figure 6
Comparison of (S)-ketoprofen binding to drug site 2 in HSA (PDB entry 7jwn) and LSA (PDB entry 6ock). The (S)-ketoprofen molecule and a molecule of a fatty acid bound to HSA are shown in stick representation with O atoms in red and C atoms in yellow, while a molecule of (S)-ketoprofen bound to LSA is shown in stick representation with O atoms in red and C atoms in gray. The colors of the helices correspond to the colors used in Fig. 2. |