view article
Figure 3
Crystallization kinetic profiles and phase diagram. (a) Time-resolved depletion profile of the urate concentration (black circles) and the corresponding pH (pink circles) evolution profile in solution crystallized from a 6.5 mM urate concentration at an initial pH of 5.5. The lines are interpolated to guide the eye. The blue-dashed line represents the solubility of UAD measured and interpolated from experimental data (Fig. S4). The red-dashed line represents the solubility of UAA measured and interpolated from experimental data (Fig. S4). (b) Phase diagram of the urate crystallization with respect to solution pH. The black, red and blue points are the measured solubilities of urate sodium monohydrate, UAA and UAD, respectively, and the corresponding lines are interpolated to guide the eye. The black empty circles represent the time-resolved depletion profile of the urate concentration, and the corresponding line is interpolated to guide the eye, representing the dynamic operating line over time.

IUCrJ
Volume 10| Part 1| January 2023| Pages 38-51
ISSN: 2052-2525
https://doi.org/10.1107/S2052252522011034