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Figure 3
TLR15TIR dimerization. (a) Gel-filtration chromatography analysis of the TLR15TIR protein. (b) The dimeric structure of TLR15TIR. Two TLR15TIR chains (TLR15TIR and its binding partner TLR15TIR′) that form a dimer are depicted as light blue and gray ribbons. The dimerization interface residues of TLR15TIR and TLR15TIR′ are colored green and orange, respectively, in the ribbon diagram, and also shown as green and orange lines, respectively. Intersubunit hydrogen bonds are represented by black dotted lines. (c) The dimerization interface of TLR15TIR. The TLR15TIR and TLR15TIR′ chains are shown as light blue and gray ribbons, respectively. The dimerization interface residues of TLR15TIR and TLR15TIR′ are colored green and orange, respectively. A detailed view of the dimerization interface is shown in Fig. S4. (d) Apolar and polar TLR15TIR residues (yellow and magenta spheres, respectively) in the dimerization interface.

IUCrJ
Volume 10| Part 3| May 2023| Pages 352-362
ISSN: 2052-2525
https://doi.org/10.1107/S2052252523002956