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Figure 6
Comparison of the TLR15TIR, TLR10TIR and TLR6TIR structures in the dimerization interfaces and intersubunit organizations. (a) Dimerization interfaces of TLR15TIR, TLR10TIR (PDB ID 2j67) and TLR6TIR (PDB ID 4om7). Dimerization interface residues are colored green in the TLRTIR structure (light blue ribbons). (b) Dimeric organization of TLR15TIR (light blue ribbons and blue Cα traces) in comparison with that of TLR10TIR (left; salmon ribbons and magenta Cα traces; PDB ID 2j67) or TLR6TIR (right; salmon ribbons and magenta Cα traces; PDB ID 4om7). Dimerization interface residues are highlighted in green in the TLR15TIR monomer structure shown as ribbons. The TLRTIR dimer structures are superimposed using the TLRTIR monomers shown as ribbons. Orientation differences are indicated by double-headed arrows.

IUCrJ
Volume 10| Part 3| May 2023| Pages 352-362
ISSN: 2052-2525