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Figure 2
The FucO dimer. (a) Both subunits are in their closed conformation (PDB entry 5br4). The upper subunit is shown in side view, such that the NAD-binding groove is seen `end-on'. The N-terminal NAD-binding domain is brown. The C-terminal Fe2+-binding domain is green. The other subunit of the dimer is shown in light green. NAD+ (purple sticks) as bound in the groove between the two domains of the upper subunit is also shown. Asn151 (of the N-terminal NAD-binding domain) and Leu259 (of the C-terminal Fe2+-binding domain) are shown in black sticks. (b) Standard view (the NAD-binding groove is seen from above) of the upper subunit of panel (a), obtained by 90° rotation around the horizontal direction with respect to the view shown in panel (a). The catalytic site is near the nicotinamide moiety of NAD+ (purple sticks), which is marked by an arrow.

IUCrJ
Volume 10| Part 4| July 2023| Pages 437-447
ISSN: 2052-2525
https://doi.org/10.1107/S205225252300444X