view article
Figure 4
Calculated structural modelling of potent F-actin-binding proteins. (a) The proposed IMP–actin binding model from the HDOCK server with a docking score of −155.95 and a confidence score of 0.530. The F-actin model is coloured blue, while the IMP model is coloured red. (b) The proposed TLNRD1–actin binding model from the HDOCK server with a docking score of −262.13 and a confidence score of 0.904. The F-actin model is coloured blue, while the TLNRD1 model is coloured light green. (c) The proposed TLNRD1_4H–actin binding model from the HDOCK server with a docking score of −260.80 and a confidence score of 0.902. The F-actin model is coloured blue, while the TLNRD1_4H model is coloured dark green. (d) The alignment of all docking ligands (IMP, TLNRD1, TLNRD1_4H and IMP/PHYL1) to F-actin (solid ribbons) with the electron-density maps from the PDB structures.

IUCrJ
Volume 11| Part 3| May 2024| Pages 384-394
ISSN: 2052-2525
https://doi.org/10.1107/S2052252524003075