Nanostructure and dynamics of N-truncated copper amyloid-β peptides from advanced X-ray absorption fine structure

Ekanayake, R.S.K.; Streltsov, V.A.; Best, S.P.; Chantler, C.T.

doi:10.1107/S2052252524001830

Figure 2
Individual EXAFS spectra of Cu^II $[{\rm A}\beta_{4-16_{z}}(z = 1,2,3)]$ , Cu^II $[{\rm A}\beta_{4-12_{z}}(z = 1)]$ and Cu^II $[{\rm A}\beta_{4-8_{z}}(z = 1,2,3)]$ and their fits in (a) k space and (b) R space. Fits are generated from experimental data and propagated uncertainties using eFEFFit XAFS analysis. Some measurements were truncated at higher k due to statistical noise. The fitted individual structures are highly consonant within noise and within estimated uncertainty. The data are obviously limited by noise for the ranges, so the fits should also be; but the fits remain detailed and accurate. The transforms are more accurate and more self-similar than Streltsov et al. (2018

). Hence, the accuracy of the results and the significance of the conclusions are dramatically improved.