The ABC toxin complex from Yersinia entomophaga can package three different cytotoxic components expressed from distinct genetic loci in an unfolded state: the structures of both shell and cargo

Busby, J.N.; Trevelyan, S.; Pegg, C.L.; Kerr, E.D.; Schulz, B.L.; Chassagnon, I.; Landsberg, M.J.; Weston, M.K.; Hurst, M.R.H.; Lott, J.S.

doi:10.1107/S2052252524001969

Figure 1
(a) Crystal structure of YenB/YenC3^NTD, coloured from blue at the N-terminus to red at the C-terminus. YenB is highlighted in green and YenC3^NTD in blue. (b) Strands of the β-sheet shell around the central cavity, coloured as in (a). The β-propeller domain is highlighted in orange. Surface representations showing (c) the exterior and a vertical slice through showing (d) the internal cavity. YenB is shown in green and YenC3^NTD is shown in blue.

IUCrJ

Volume 11| Part 3| May 2024| Pages 299-308

ISSN: 2052-2525

https://doi.org/10.1107/S2052252524001969

BIOLOGY | MEDICINE

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