journal menu
![[Figure 2]](be5297fig2mag.jpg)
|
|
Figure 2
Specific methodologies underpinning microcrystallography (µxt). (a)–(c) Crystallogenesis requires approaches that differ from `traditional' methods, including (a) in-chip and (b) in-cell crystallization, or (c) in-LCP crystallization and the HiLiDe method for membrane proteins. Presentation of the crystals to an X-ray beam requires specific approaches using (d) meshes, grids and small supports; (e) large-area chips; (f) jets; (g) or other combined technologies. (h)–(j) Diffraction experiments are possible thanks to the development of microfocus beamlines at synchrotrons and free-electron laser facilities across the world. (j) MicroED emerges as an alternative to X-ray diffraction for the smallest microcrystals. Figure adapted from the literature (Gicquel et al., 2018  ; Heymann et al., 2014; De Wijn et al., 2019; Schönherr et al., 2015; Manji & Friesen, 2001; Hasegawa et al., 2011; Båth, 2022; Trampari et al., 2021; Illava et al., 2021; Owen et al., 2017; Oberthuer et al., 2017; Beyerlein et al., 2017; Tsujino & Tomizaki, 2016) with permission. Images in (d) and (f) were provided by MiTeGen and SerialX, respectively. |
![[Figure 2]](be5297fig2.jpg)
ISSN: 2052-2525
NEUTRON | SYNCHROTRON
Open 
access
access
