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Figure 5
Denoising a medium-resolution map. The map of Sec61 membrane channel from Saccharomyces cerevisiae (Itskanov et al., 2021BB15) and its fragment focused on one selected internal channel helix with the fitted atomistic model are visualized. This map is part of the test set and has a resolution of 4 Å. The noisy map, constructed as a mean of two half-maps, is presented in (a). The final published map is shown in (b). The noisy sharpened mean map is presented in (c). The denoised and sharpened mean map is presented in (d). The denoised map preserves lower-resolution motifs (the black-arrow marked α-helix) and high-resolution details (the inset), while the noise is substantially reduced. Contouring was tuned to make the maps most similar.

IUCrJ
Volume 11| Part 5| September 2024| Pages 821-830
ISSN: 2052-2525
https://doi.org/10.1107/S2052252524005918