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Figure 1
Structure of sEH. (Left) Structure of inhibitor-bound sEH solved at cryogenic temperature (PDB entry 5ake; Öster et al., 2015BB35). The active site with the bound compound 4 (purple) is located in the C-terminal domain. (Right) Zoom-in of the active site where the compound (purple) interacts with the catalytic triad (Asp335, Tyr383 and Tyr466).

IUCrJ
Volume 11| Part 5| September 2024| Pages 831-842
ISSN: 2052-2525
https://doi.org/10.1107/S2052252524006134