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Figure 2
Microcrystallization and data collection workflow. Panel 1: production of crystal seeds from macro crystals using seed beads and vortexing. Panel 2: hybrid crystallization used for screening to find optimal batch crystallization conditions. Panel 3: batch crystallization with seeding and vortexing to induce nucleation. Panel 4: soaking of compound into the microcrystals. Panel 5: dispensing of soaked crystals onto the chip and sealing. Panel 6: fixed-target raster grid-scan data collection on ligand-soaked crystals at a synchrotron source. |
IUCrJ
ISSN: 2052-2525
BIOLOGY | MEDICINE
Open
access
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