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Figure 2
Neu5Ac transport mechanism in Gram-negative bacteria. (1) Porins located in the outer membrane facilitate the transport of Neu5Ac into the periplasmic space. (2) and (4) SatA proteins bind to Neu5Ac molecules and are then associated with the ABC transporter. SiaP proteins (3) also bind to Neu5Ac and assist TRAP transporters (6) in translocating Neu5Ac into the cytoplasm. (5) The SSS transporter facilitates the movement of cargo molecules across the membrane using the energy provided by an ion gradient.

IUCrJ
Volume 11| Part 5| September 2024| Pages 664-674
ISSN: 2052-2525
https://doi.org/10.1107/S2052252524005360