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Figure 6
Serial crystallography structure of r-ATX in the space group P1. (a) and (c) display the in situ determined structure, (b) and (d) display the structure determined from serial cryo data collection. (a) Overall 2Fo − Fc electron density map at the 1.2σ level in blue overlaid onto the r-ATX model in the magenta sticks representation. (c) 2Fo − Fc electron density map in blue for the oxysterol moiety bound in the allosteric tunnel of the r-ATX model shown in magenta. (b) Overall 2Fo − Fc electron density map at the 1.2σ level in purple overlaid onto the r-ATX model in ocean green sticks representation. (d) 2Fo − Fc electron density map in purple for the oxysterol moiety bound in the allosteric tunnel of r-ATX model shown in ocean green.

IUCrJ
Volume 11| Part 5| September 2024| Pages 780-791
ISSN: 2052-2525
https://doi.org/10.1107/S2052252524005785