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Figure 11
Detailed view of the section of the deposited model where conkit-validate erroneously identified a potential sequence-register error in human calcineurin (PDB entry 5c1v). (a) The deposited structure is shown in grey with the fold-switching region (residues 309–340) shown in a rainbow spectrum, where blue indicates its N-terminal part and red indicates the C-terminus. The density map for the deposited structure is represented as a transparent grey surface and the contour level was set to 0.25. (b) A close-up of the fold-switching region in chain B of the deposited structure and the associated density. (c) The automated attempt at fixing the potential sequence-register error identified by conkit-validate. (d) A close-up of the fold-switching region in chain B of the attempted fix.

IUCrJ
Volume 11| Part 6| November 2024|
ISSN: 2052-2525
https://doi.org/10.1107/S2052252524009114