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Figure 9
Detailed views of portions of deposited cryo-EM structures in which a possible sequence-register error was detected using conkit-validate. (a) The error corresponds to PDB entry 3j9z chain SB residues 7–24, and residues 14, 15 and 17 have been highlighted. (b) The error corresponds to PDB entry 6gz3 chain BJ residues 153–180, and residues 156, 159 and 165 have been highlighted. In each case, a mask of 2.5 Å around the model was applied; the original deposition is coloured red, with the structure corrected with the sequence register suggested by conkit-validate in blue. The density map for the deposited structure is represented as a transparent grey surface with the contour level set to 0.035 in (a) and 2.2 in (b).

ISSN: 2052-2525