Figure 6
Disease-associated TOM mutations. (a) Cartoon representation of the Drosophila Tom40–Tom7 interface. Disease-associated mutations are depicted as yellow spheres. (b) Sequence logo (Crooks et al., 2004) showing the conservation (overall height) and residue prevalence of sections of the Tom40 and Tom7 protein sequences. Residue numbering is for the human proteins. Amino-acid residues that are mutated in disease conditions are colored yellow and marked with boxes. This image was created with WebLogo. |