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Figure 1
Two approaches for sample delivery at ESRF beamline ID29. (a) Fixed target. The microcrystal slurry is sandwiched between two Mylar films sealed by a metal mount and aligned in front of the X-ray beam. The chip is raster-scanned serially at pre-defined positions as shown by black dots. (b) Schematic depiction of the tape-drive setup. The microcrystal slurry is applied to a tape drive which transports the sample to the X-ray beam. Light from a laser or from a light-emitting diode (LED) can be used to initiate light-driven reactions in photoactive proteins before the crystals reach the X-ray interaction region.

IUCrJ
Volume 12| Part 1| January 2025|
ISSN: 2052-2525
https://doi.org/10.1107/S2052252524010868