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Figure 10
Performance of 2DTM metrics when searching a mixed-particle montage using the clathrin monomer as the template. For each row, the figures show (from left to right) an example mixture montage containing 50 clathrin monomers and 50 proteasomes (a) or 50 mature 60S ribosomes (b), a scatter plot comparing 2DTM SNR and z-score, and ROC curves of the three metrics for ten 10 × 10 mixture montages [which correspond to 500 simulated clathrin particles mixed with 500 proteasome particles (or 60S particles)].

IUCrJ
Volume 12| Part 2| March 2025|
ISSN: 2052-2525
https://doi.org/10.1107/S2052252524011771