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Figure 21
Calculating the 2DTM p-value threshold using multiple hypothesis testing. In this example, we calculated the 2DTM p-values for a noisy image from the yeast lamella data set (148_Mar12_12.23.52_161_0.mrc) with a noise variance ratio of 0.5. We estimated 200 particles and calculated the adjusted p-values using the Benjamini–Hochberg procedure to control the false-discovery rate (FDR) at an α value of 0.05. Using this method, we identified 166 of 176 targets.

IUCrJ
Volume 12| Part 2| March 2025|
ISSN: 2052-2525
https://doi.org/10.1107/S2052252524011771