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Figure 1
Non-monotonic changes in diffraction intensity from stationary, room-temperature crystals at 200 kV. For representative crystals of (a) biotin, (c) Cu(II)-serine, (e) Zn(II)-me­thio­nine, (g) Zn(II)-histidine and (i) Co(II)-porphyrin: initial diffraction pattern and frames acquired following an accumulated fluence of (from left to right) 0.5, 1.0, 1.5 and 2.0 e− Å−2; plot of normalized total reflection intensity (left-hand y axis) as a function of accumulated fluence; and discretized plot of values of the derivative of this curve with respect to fluence (right-hand y axis). Plots of the average standard deviation of first-derivative values in each such discrete bin for (b) biotin, (d) Cu(II)-serine, (f) Zn(II)-me­thio­nine, (h) Zn(II)-histidine and (j) Co(II)-porphyrin interrogated at 200 kV and room temperature. Error bars are equal to one standard deviation from the mean. Inset are ORTEP diagrams of a representative atomic structure solution determined by MicroED for each compound.

IUCrJ
Volume 12| Part 2| March 2025|
ISSN: 2052-2525
https://doi.org/10.1107/S2052252524012132