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Figure 4
Time-resolved binding of NAG1 to hen egg-white lysozyme. Panels show electron density (2Fo − Fc, contoured at 1σ), difference density (Fo − Fc, contoured at 3σ) and isomorphous difference density (Fo − Fo, contoured at 2.5σ) of NAG1 binding. Refined occupancies are indicated in parentheses. Although 0, 8 and 50 ms refinements give nonzero occupancy, there is no evidence for binding, even at lower σ electron-density thresholds.

IUCrJ
Volume 12| Part 3| May 2025|
ISSN: 2052-2525
https://doi.org/10.1107/S205225252500288X