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Figure 1
Schematic comparison of serial femtosecond crystallography (SFX) and serial synchrotron crystallography (SSX). In SFX (top), femtosecond X-ray pulses enable diffraction before radiation damage develops, yielding largely damage-free datasets. In SSX (bottom), longer exposures can induce transient heating and molecular motion during irradiation, leading to global lattice disorder and attenuation of high-resolution Bragg intensities (Bragg termination). The two-dimensional plots of central hk0 sections of the reciprocal lattice were generated using render_hkl from CrystFEL (White et al., 2012View full citation) for representative SFX and SSX datasets, respectively; their use here is purely schematic. Created in bioRender (https://biorender.com).

IUCrJ
ISSN: 2052-2525