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Figure 3
Automated microbatch-under-oil phase diagrams to rationalize serial crystallography sample preparation. (a, b) Phycocyanin phase diagrams obtained (a) without addition of seed stock and (b) with seed stock added. (c) Xylanase phase diagram obtained without the addition of seed stock, where the highlighted well (15.95 mg ml−1 xylanase in 4.46 M sodium formate) was used to generate seed stock for the subsequent xylanase phase diagram (d) with seed stock added. The highlighted well in (d) (20.1 mg ml−1 xylanase in 3.54 M sodium formate) was used for the xylanase seed-stock dilution series (e) using a cross-matrix experiment on the Oryx8 crystallization robot.

IUCrJ
Volume 13| Part 2| March 2026| Pages 159-168
ISSN: 2052-2525