Supporting information
Crystallographic Information File (CIF) https://doi.org/10.1107/S1600536807043085/fi2043sup1.cif | |
Structure factor file (CIF format) https://doi.org/10.1107/S1600536807043085/fi2043Isup2.hkl |
CCDC reference: 663720
4-methoxybenzohydrazide (0.01 mol,1.66 g) was dissolved in anhydrous ethanol (50 ml), and 2-nitrobenzaldehyde (Shanghai Chemical Reagents Company, 99%, 0.01 mol, 1.51 g) was added. The reaction mixture was refluxed for 4 h with stirring, then the resulting precipitate was collected by filtration, washed several times with ethanol and dried in vacuo (yield 85%). The compound (1.0 mmol,0.30 g) was dissolved in dimethylformamide (15 ml) and kept at room temperature for 30 d to obtain yellow single crystals suitable for X-ray diffraction.
Friedel pairs were merged prior to refinement. All H atoms were positioned geometrically and treated as riding on their parent atoms,with C—H(methyl) = 0.96 Å, C—H(aromatic,imine) = 0.93 Å, and N—H = 0.86 Å and with Uiso(H) =1.5Ueq(Cmethyl,) and 1.2Ueq(Caromatic,Cimine,N).
The chemistry of aroylhydrazones continues to attract much attention due to their coordination ability to metal ions (Singh et al., 1982; Salem, 1998) and their biological activity (Singh et al., 1982; Carcelli et al., 1995). As an extension of the work on the structural characterization of aroylhydrazone derivatives, the title compound, (I),was synthesized and its crystal structure is reported here.
There are two crystallographically independent molecules in the asymmetric unit (Fig. 1). The conformations of the two molecules are almost the same. Both display trans conformation with respect to the C9=N2 and C24=N5 double bond. The benzene rings of the two molecules, C2—C7(A), C10—C15(B), C17—C22(C) and C25—C30(D), make dihedral angles of 86.75 (9)° (A;B), but 8.3 (2)°(C;D)·The crystal structure is stabilized by intermolecular N—H···O hydrogen bonds, which yield chains running along b. (Table 1. and Fig. 2).
For related literature, see: Carcelli et al. (1995); Salem (1998); Singh et al. (1982).
Data collection: APEX2 (Bruker, 2005); cell refinement: SAINT (Bruker, 2005); data reduction: SAINT (Bruker, 2005); program(s) used to solve structure: SHELXS97 (Sheldrick, 1997a); program(s) used to refine structure: SHELXL97 (Sheldrick, 1997a); molecular graphics: SHELXTL (Sheldrick, 1997b); software used to prepare material for publication: SHELXTL (Sheldrick, 1997b).
C15H13N3O4 | F(000) = 1248 |
Mr = 299.28 | Dx = 1.388 Mg m−3 |
Orthorhombic, Pca21 | Mo Kα radiation, λ = 0.71073 Å |
Hall symbol: P 2c -2ac | Cell parameters from 3567 reflections |
a = 27.3272 (15) Å | θ = 2.4–21.4° |
b = 4.8389 (3) Å | µ = 0.10 mm−1 |
c = 21.6639 (12) Å | T = 273 K |
V = 2864.7 (3) Å3 | Block, yellow |
Z = 8 | 0.35 × 0.23 × 0.13 mm |
Bruker APEX II CCD diffractometer | 2598 independent reflections |
Radiation source: fine-focus sealed tube | 2106 reflections with I > 2σ(I) |
Graphite monochromator | Rint = 0.055 |
φ & ω scans | θmax = 25.0°, θmin = 1.5° |
Absorption correction: multi-scan (SADABS; Sheldrick, 2003) | h = −32→32 |
Tmin = 0.966, Tmax = 0.983 | k = −5→5 |
24492 measured reflections | l = −25→25 |
Refinement on F2 | Secondary atom site location: difference Fourier map |
Least-squares matrix: full | Hydrogen site location: inferred from neighbouring sites |
R[F2 > 2σ(F2)] = 0.037 | H-atom parameters constrained |
wR(F2) = 0.094 | w = 1/[σ2(Fo2) + (0.055P)2] where P = (Fo2 + 2Fc2)/3 |
S = 1.08 | (Δ/σ)max < 0.001 |
2598 reflections | Δρmax = 0.15 e Å−3 |
400 parameters | Δρmin = −0.11 e Å−3 |
1 restraint | Extinction correction: SHELXL97, Fc*=kFc[1+0.001xFc2λ3/sin(2θ)]-1/4 |
Primary atom site location: structure-invariant direct methods | Extinction coefficient: 0.0052 (8) |
C15H13N3O4 | V = 2864.7 (3) Å3 |
Mr = 299.28 | Z = 8 |
Orthorhombic, Pca21 | Mo Kα radiation |
a = 27.3272 (15) Å | µ = 0.10 mm−1 |
b = 4.8389 (3) Å | T = 273 K |
c = 21.6639 (12) Å | 0.35 × 0.23 × 0.13 mm |
Bruker APEX II CCD diffractometer | 2598 independent reflections |
Absorption correction: multi-scan (SADABS; Sheldrick, 2003) | 2106 reflections with I > 2σ(I) |
Tmin = 0.966, Tmax = 0.983 | Rint = 0.055 |
24492 measured reflections |
R[F2 > 2σ(F2)] = 0.037 | 1 restraint |
wR(F2) = 0.094 | H-atom parameters constrained |
S = 1.08 | Δρmax = 0.15 e Å−3 |
2598 reflections | Δρmin = −0.11 e Å−3 |
400 parameters |
Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes. |
Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger. |
x | y | z | Uiso*/Ueq | ||
O1 | 0.95758 (9) | 0.5777 (5) | 0.99874 (14) | 0.0730 (8) | |
O2 | 0.79909 (9) | 0.1002 (6) | 0.81382 (13) | 0.0818 (8) | |
O3 | 1.07001 (10) | −0.5271 (7) | 1.21363 (14) | 0.0852 (9) | |
O4 | 1.01349 (9) | −0.3168 (7) | 1.16428 (15) | 0.0897 (10) | |
O5 | 0.22355 (8) | 1.3185 (4) | −0.03675 (13) | 0.0624 (7) | |
O6 | 0.04707 (8) | 0.7561 (6) | −0.17868 (12) | 0.0741 (8) | |
O7 | 0.32068 (10) | 0.2884 (7) | 0.22193 (14) | 0.0894 (9) | |
O8 | 0.26593 (11) | 0.4585 (7) | 0.16330 (14) | 0.0954 (10) | |
N1 | 0.98150 (9) | 0.1336 (5) | 0.99582 (14) | 0.0511 (7) | |
H1 | 0.9759 | −0.0309 | 0.9826 | 0.061* | |
N2 | 1.02079 (9) | 0.1816 (6) | 1.03432 (13) | 0.0511 (7) | |
N3 | 1.05595 (10) | −0.3480 (6) | 1.17783 (14) | 0.0568 (7) | |
N4 | 0.23202 (9) | 0.8791 (5) | −0.00297 (12) | 0.0470 (6) | |
H4 | 0.2224 | 0.7104 | −0.0057 | 0.056* | |
N5 | 0.27059 (9) | 0.9449 (5) | 0.03510 (12) | 0.0465 (6) | |
N6 | 0.30788 (11) | 0.4463 (6) | 0.18136 (13) | 0.0573 (7) | |
C1 | 0.75747 (14) | 0.2779 (11) | 0.8092 (2) | 0.0971 (15) | |
H1A | 0.7403 | 0.2803 | 0.8478 | 0.146* | |
H1B | 0.7361 | 0.2112 | 0.7773 | 0.146* | |
H1C | 0.7681 | 0.4617 | 0.7991 | 0.146* | |
C2 | 0.83484 (13) | 0.1711 (8) | 0.85484 (17) | 0.0591 (9) | |
C3 | 0.87762 (14) | 0.0170 (8) | 0.85072 (19) | 0.0692 (10) | |
H3 | 0.8807 | −0.1200 | 0.8209 | 0.083* | |
C4 | 0.91548 (14) | 0.0688 (7) | 0.89123 (17) | 0.0614 (9) | |
H4A | 0.9440 | −0.0352 | 0.8886 | 0.074* | |
C5 | 0.91161 (11) | 0.2735 (6) | 0.93575 (15) | 0.0479 (8) | |
C6 | 0.86918 (12) | 0.4255 (7) | 0.93821 (17) | 0.0575 (9) | |
H6 | 0.8663 | 0.5661 | 0.9673 | 0.069* | |
C7 | 0.83074 (13) | 0.3740 (8) | 0.89850 (17) | 0.0639 (10) | |
H7 | 0.8021 | 0.4771 | 0.9014 | 0.077* | |
C8 | 0.95202 (11) | 0.3410 (6) | 0.97897 (15) | 0.0493 (8) | |
C9 | 1.03790 (11) | −0.0312 (7) | 1.06142 (15) | 0.0475 (8) | |
H9 | 1.0226 | −0.2017 | 1.0573 | 0.057* | |
C10 | 1.08216 (11) | −0.0030 (6) | 1.09922 (14) | 0.0452 (7) | |
C11 | 1.09264 (11) | −0.1602 (7) | 1.15167 (15) | 0.0476 (8) | |
C12 | 1.13661 (12) | −0.1393 (8) | 1.18240 (17) | 0.0619 (9) | |
H12 | 1.1428 | −0.2501 | 1.2166 | 0.074* | |
C13 | 1.17137 (13) | 0.0459 (9) | 1.16240 (19) | 0.0703 (11) | |
H13 | 1.2010 | 0.0622 | 1.1831 | 0.084* | |
C14 | 1.16188 (13) | 0.2054 (8) | 1.11180 (19) | 0.0656 (10) | |
H14 | 1.1851 | 0.3327 | 1.0985 | 0.079* | |
C15 | 1.11838 (12) | 0.1803 (7) | 1.08016 (17) | 0.0560 (9) | |
H15 | 1.1131 | 0.2883 | 1.0453 | 0.067* | |
C16 | 0.01518 (13) | 0.5396 (9) | −0.1618 (2) | 0.0761 (12) | |
H16A | 0.0332 | 0.3696 | −0.1594 | 0.114* | |
H16B | −0.0102 | 0.5224 | −0.1922 | 0.114* | |
H16C | 0.0009 | 0.5794 | −0.1223 | 0.114* | |
C17 | 0.08517 (11) | 0.8199 (7) | −0.14052 (16) | 0.0506 (8) | |
C18 | 0.09396 (11) | 0.7002 (7) | −0.08400 (16) | 0.0525 (8) | |
H18 | 0.0729 | 0.5661 | −0.0686 | 0.063* | |
C19 | 0.13441 (10) | 0.7810 (7) | −0.05040 (15) | 0.0491 (8) | |
H19 | 0.1406 | 0.6972 | −0.0126 | 0.059* | |
C20 | 0.16590 (11) | 0.9834 (6) | −0.07158 (14) | 0.0435 (7) | |
C21 | 0.15563 (12) | 1.1059 (7) | −0.12792 (15) | 0.0544 (9) | |
H21 | 0.1758 | 1.2463 | −0.1425 | 0.065* | |
C22 | 0.11605 (12) | 1.0229 (8) | −0.16261 (16) | 0.0593 (9) | |
H22 | 0.1101 | 1.1035 | −0.2009 | 0.071* | |
C23 | 0.20924 (10) | 1.0772 (6) | −0.03599 (15) | 0.0451 (7) | |
C24 | 0.28988 (11) | 0.7390 (7) | 0.06273 (16) | 0.0470 (7) | |
H24 | 0.2768 | 0.5626 | 0.0583 | 0.056* | |
C25 | 0.33316 (11) | 0.7859 (6) | 0.10178 (14) | 0.0443 (7) | |
C26 | 0.34331 (11) | 0.6392 (6) | 0.15542 (15) | 0.0467 (8) | |
C27 | 0.38649 (12) | 0.6755 (8) | 0.18840 (16) | 0.0589 (9) | |
H27 | 0.3927 | 0.5705 | 0.2235 | 0.071* | |
C28 | 0.41980 (13) | 0.8683 (8) | 0.16846 (19) | 0.0650 (10) | |
H28 | 0.4490 | 0.8939 | 0.1898 | 0.078* | |
C29 | 0.40985 (12) | 1.0226 (8) | 0.11709 (18) | 0.0583 (9) | |
H29 | 0.4319 | 1.1580 | 0.1046 | 0.070* | |
C30 | 0.36755 (11) | 0.9796 (7) | 0.08357 (16) | 0.0527 (8) | |
H30 | 0.3620 | 1.0829 | 0.0480 | 0.063* |
U11 | U22 | U33 | U12 | U13 | U23 | |
O1 | 0.0890 (17) | 0.0340 (12) | 0.0960 (19) | −0.0048 (11) | −0.0347 (16) | −0.0019 (13) |
O2 | 0.0764 (17) | 0.098 (2) | 0.0704 (18) | −0.0061 (15) | −0.0289 (15) | 0.0015 (16) |
O3 | 0.0807 (17) | 0.086 (2) | 0.089 (2) | 0.0083 (16) | 0.0100 (16) | 0.0312 (18) |
O4 | 0.0496 (15) | 0.114 (2) | 0.106 (2) | −0.0133 (15) | −0.0068 (15) | 0.040 (2) |
O5 | 0.0674 (14) | 0.0349 (11) | 0.0847 (17) | −0.0063 (11) | −0.0201 (13) | 0.0019 (12) |
O6 | 0.0629 (15) | 0.0995 (19) | 0.0598 (16) | −0.0222 (14) | −0.0165 (13) | 0.0047 (14) |
O7 | 0.0940 (19) | 0.093 (2) | 0.082 (2) | 0.0037 (18) | 0.0064 (17) | 0.0429 (18) |
O8 | 0.0729 (19) | 0.131 (2) | 0.083 (2) | −0.0422 (18) | −0.0174 (16) | 0.032 (2) |
N1 | 0.0558 (16) | 0.0365 (14) | 0.0610 (17) | −0.0034 (12) | −0.0167 (14) | −0.0009 (13) |
N2 | 0.0501 (15) | 0.0481 (16) | 0.0551 (16) | −0.0064 (12) | −0.0091 (14) | 0.0029 (14) |
N3 | 0.0526 (17) | 0.0621 (19) | 0.0559 (18) | 0.0037 (14) | 0.0037 (14) | 0.0058 (17) |
N4 | 0.0526 (14) | 0.0322 (13) | 0.0563 (16) | −0.0059 (11) | −0.0174 (14) | −0.0004 (12) |
N5 | 0.0496 (15) | 0.0406 (14) | 0.0492 (15) | −0.0025 (12) | −0.0070 (13) | −0.0033 (13) |
N6 | 0.0609 (19) | 0.0612 (18) | 0.0499 (17) | −0.0041 (15) | 0.0006 (15) | 0.0051 (16) |
C1 | 0.053 (2) | 0.151 (4) | 0.087 (3) | 0.003 (3) | −0.013 (2) | 0.013 (3) |
C2 | 0.060 (2) | 0.067 (2) | 0.050 (2) | −0.0104 (19) | −0.0114 (17) | 0.0117 (19) |
C3 | 0.086 (3) | 0.059 (2) | 0.063 (2) | 0.012 (2) | −0.023 (2) | −0.0079 (19) |
C4 | 0.073 (2) | 0.049 (2) | 0.062 (2) | 0.0116 (18) | −0.0157 (19) | −0.0050 (18) |
C5 | 0.0576 (19) | 0.0326 (15) | 0.053 (2) | −0.0017 (15) | −0.0086 (15) | 0.0061 (15) |
C6 | 0.061 (2) | 0.054 (2) | 0.058 (2) | 0.0020 (17) | −0.0019 (18) | −0.0066 (17) |
C7 | 0.055 (2) | 0.078 (3) | 0.059 (2) | 0.0035 (19) | −0.0028 (18) | 0.002 (2) |
C8 | 0.0583 (19) | 0.0366 (17) | 0.053 (2) | −0.0057 (14) | −0.0072 (16) | 0.0051 (15) |
C9 | 0.0462 (17) | 0.0418 (18) | 0.0543 (19) | −0.0050 (14) | −0.0017 (15) | 0.0008 (16) |
C10 | 0.0418 (16) | 0.0454 (17) | 0.0485 (19) | −0.0002 (14) | −0.0006 (15) | −0.0027 (15) |
C11 | 0.0411 (17) | 0.0489 (19) | 0.0527 (19) | −0.0004 (15) | −0.0028 (15) | −0.0055 (16) |
C12 | 0.057 (2) | 0.066 (2) | 0.062 (2) | 0.0022 (18) | −0.0077 (18) | −0.0009 (19) |
C13 | 0.045 (2) | 0.089 (3) | 0.078 (3) | −0.011 (2) | −0.0144 (19) | −0.005 (2) |
C14 | 0.053 (2) | 0.074 (2) | 0.070 (3) | −0.0181 (19) | −0.0002 (19) | −0.007 (2) |
C15 | 0.0503 (19) | 0.060 (2) | 0.058 (2) | −0.0079 (16) | 0.0022 (17) | 0.0000 (17) |
C16 | 0.052 (2) | 0.085 (3) | 0.091 (3) | −0.011 (2) | −0.012 (2) | −0.005 (2) |
C17 | 0.0467 (18) | 0.062 (2) | 0.0436 (18) | −0.0023 (16) | −0.0065 (15) | −0.0039 (17) |
C18 | 0.0504 (19) | 0.051 (2) | 0.056 (2) | −0.0097 (16) | 0.0023 (17) | 0.0049 (16) |
C19 | 0.0513 (18) | 0.0500 (18) | 0.0461 (19) | −0.0035 (16) | −0.0069 (15) | 0.0084 (15) |
C20 | 0.0485 (17) | 0.0347 (15) | 0.0472 (18) | 0.0015 (13) | −0.0025 (15) | −0.0014 (14) |
C21 | 0.056 (2) | 0.0516 (19) | 0.056 (2) | −0.0057 (16) | −0.0042 (17) | 0.0069 (17) |
C22 | 0.062 (2) | 0.069 (2) | 0.047 (2) | −0.0058 (19) | −0.0112 (17) | 0.0137 (18) |
C23 | 0.0484 (17) | 0.0362 (16) | 0.0505 (19) | 0.0017 (14) | −0.0049 (15) | −0.0007 (15) |
C24 | 0.0481 (17) | 0.0445 (18) | 0.0483 (18) | −0.0054 (15) | −0.0048 (15) | −0.0032 (15) |
C25 | 0.0457 (17) | 0.0410 (17) | 0.0462 (18) | 0.0032 (14) | −0.0023 (15) | −0.0051 (15) |
C26 | 0.0469 (17) | 0.0485 (18) | 0.0446 (18) | 0.0020 (15) | −0.0028 (14) | −0.0037 (15) |
C27 | 0.061 (2) | 0.060 (2) | 0.056 (2) | 0.0060 (18) | −0.0153 (18) | 0.0018 (18) |
C28 | 0.0437 (18) | 0.083 (3) | 0.069 (2) | −0.0079 (19) | −0.0109 (18) | −0.010 (2) |
C29 | 0.048 (2) | 0.063 (2) | 0.064 (2) | −0.0110 (17) | 0.0025 (17) | −0.0041 (19) |
C30 | 0.0527 (19) | 0.053 (2) | 0.0521 (19) | −0.0038 (16) | 0.0004 (16) | 0.0003 (16) |
O1—C8 | 1.232 (4) | C10—C15 | 1.392 (4) |
O2—C2 | 1.364 (4) | C10—C11 | 1.397 (5) |
O2—C1 | 1.430 (5) | C11—C12 | 1.377 (5) |
O3—N3 | 1.225 (4) | C12—C13 | 1.376 (5) |
O4—N3 | 1.206 (4) | C12—H12 | 0.9300 |
O5—C23 | 1.232 (3) | C13—C14 | 1.365 (6) |
O6—C17 | 1.365 (4) | C13—H13 | 0.9300 |
O6—C16 | 1.411 (5) | C14—C15 | 1.378 (5) |
O7—N6 | 1.216 (4) | C14—H14 | 0.9300 |
O8—N6 | 1.213 (4) | C15—H15 | 0.9300 |
N1—C8 | 1.338 (4) | C16—H16A | 0.9600 |
N1—N2 | 1.379 (3) | C16—H16B | 0.9600 |
N1—H1 | 0.8600 | C16—H16C | 0.9600 |
N2—C9 | 1.274 (4) | C17—C18 | 1.376 (5) |
N3—C11 | 1.467 (4) | C17—C22 | 1.381 (5) |
N4—C23 | 1.348 (4) | C18—C19 | 1.380 (4) |
N4—N5 | 1.376 (3) | C18—H18 | 0.9300 |
N4—H4 | 0.8600 | C19—C20 | 1.382 (4) |
N5—C24 | 1.276 (4) | C19—H19 | 0.9300 |
N6—C26 | 1.458 (4) | C20—C21 | 1.385 (4) |
C1—H1A | 0.9600 | C20—C23 | 1.484 (4) |
C1—H1B | 0.9600 | C21—C22 | 1.377 (5) |
C1—H1C | 0.9600 | C21—H21 | 0.9300 |
C2—C7 | 1.368 (5) | C22—H22 | 0.9300 |
C2—C3 | 1.389 (5) | C24—C25 | 1.472 (4) |
C3—C4 | 1.380 (5) | C24—H24 | 0.9300 |
C3—H3 | 0.9300 | C25—C30 | 1.385 (4) |
C4—C5 | 1.386 (5) | C25—C26 | 1.390 (4) |
C4—H4A | 0.9300 | C26—C27 | 1.391 (4) |
C5—C6 | 1.374 (4) | C27—C28 | 1.373 (5) |
C5—C8 | 1.484 (4) | C27—H27 | 0.9300 |
C6—C7 | 1.380 (5) | C28—C29 | 1.367 (5) |
C6—H6 | 0.9300 | C28—H28 | 0.9300 |
C7—H7 | 0.9300 | C29—C30 | 1.381 (5) |
C9—C10 | 1.467 (4) | C29—H29 | 0.9300 |
C9—H9 | 0.9300 | C30—H30 | 0.9300 |
C2—O2—C1 | 117.7 (3) | C14—C13—H13 | 120.3 |
C17—O6—C16 | 118.8 (3) | C12—C13—H13 | 120.3 |
C8—N1—N2 | 120.5 (3) | C13—C14—C15 | 120.9 (3) |
C8—N1—H1 | 119.8 | C13—C14—H14 | 119.6 |
N2—N1—H1 | 119.8 | C15—C14—H14 | 119.6 |
C9—N2—N1 | 115.4 (3) | C14—C15—C10 | 121.5 (3) |
O4—N3—O3 | 123.0 (3) | C14—C15—H15 | 119.3 |
O4—N3—C11 | 119.1 (3) | C10—C15—H15 | 119.3 |
O3—N3—C11 | 117.9 (3) | O6—C16—H16A | 109.5 |
C23—N4—N5 | 120.5 (2) | O6—C16—H16B | 109.5 |
C23—N4—H4 | 119.8 | H16A—C16—H16B | 109.5 |
N5—N4—H4 | 119.8 | O6—C16—H16C | 109.5 |
C24—N5—N4 | 114.6 (2) | H16A—C16—H16C | 109.5 |
O8—N6—O7 | 122.4 (3) | H16B—C16—H16C | 109.5 |
O8—N6—C26 | 118.2 (3) | O6—C17—C18 | 125.3 (3) |
O7—N6—C26 | 119.3 (3) | O6—C17—C22 | 114.7 (3) |
O2—C1—H1A | 109.5 | C18—C17—C22 | 120.1 (3) |
O2—C1—H1B | 109.5 | C17—C18—C19 | 119.3 (3) |
H1A—C1—H1B | 109.5 | C17—C18—H18 | 120.3 |
O2—C1—H1C | 109.5 | C19—C18—H18 | 120.3 |
H1A—C1—H1C | 109.5 | C18—C19—C20 | 121.6 (3) |
H1B—C1—H1C | 109.5 | C18—C19—H19 | 119.2 |
O2—C2—C7 | 124.9 (3) | C20—C19—H19 | 119.2 |
O2—C2—C3 | 115.2 (4) | C19—C20—C21 | 118.0 (3) |
C7—C2—C3 | 119.9 (3) | C19—C20—C23 | 122.8 (3) |
C4—C3—C2 | 119.5 (4) | C21—C20—C23 | 119.2 (3) |
C4—C3—H3 | 120.2 | C22—C21—C20 | 121.0 (3) |
C2—C3—H3 | 120.2 | C22—C21—H21 | 119.5 |
C3—C4—C5 | 121.0 (4) | C20—C21—H21 | 119.5 |
C3—C4—H4A | 119.5 | C21—C22—C17 | 119.9 (3) |
C5—C4—H4A | 119.5 | C21—C22—H22 | 120.1 |
C6—C5—C4 | 118.3 (3) | C17—C22—H22 | 120.1 |
C6—C5—C8 | 119.0 (3) | O5—C23—N4 | 122.3 (3) |
C4—C5—C8 | 122.6 (3) | O5—C23—C20 | 122.4 (3) |
C5—C6—C7 | 121.4 (3) | N4—C23—C20 | 115.3 (2) |
C5—C6—H6 | 119.3 | N5—C24—C25 | 118.8 (3) |
C7—C6—H6 | 119.3 | N5—C24—H24 | 120.6 |
C2—C7—C6 | 119.9 (3) | C25—C24—H24 | 120.6 |
C2—C7—H7 | 120.1 | C30—C25—C26 | 116.6 (3) |
C6—C7—H7 | 120.1 | C30—C25—C24 | 119.1 (3) |
O1—C8—N1 | 121.9 (3) | C26—C25—C24 | 124.2 (3) |
O1—C8—C5 | 121.0 (3) | C25—C26—C27 | 122.3 (3) |
N1—C8—C5 | 117.1 (3) | C25—C26—N6 | 121.1 (3) |
N2—C9—C10 | 119.0 (3) | C27—C26—N6 | 116.5 (3) |
N2—C9—H9 | 120.5 | C28—C27—C26 | 119.1 (3) |
C10—C9—H9 | 120.5 | C28—C27—H27 | 120.4 |
C15—C10—C11 | 116.3 (3) | C26—C27—H27 | 120.4 |
C15—C10—C9 | 118.7 (3) | C29—C28—C27 | 119.7 (3) |
C11—C10—C9 | 124.9 (3) | C29—C28—H28 | 120.2 |
C12—C11—C10 | 122.1 (3) | C27—C28—H28 | 120.2 |
C12—C11—N3 | 117.1 (3) | C28—C29—C30 | 120.8 (3) |
C10—C11—N3 | 120.7 (3) | C28—C29—H29 | 119.6 |
C13—C12—C11 | 119.9 (3) | C30—C29—H29 | 119.6 |
C13—C12—H12 | 120.1 | C29—C30—C25 | 121.4 (3) |
C11—C12—H12 | 120.1 | C29—C30—H30 | 119.3 |
C14—C13—C12 | 119.3 (3) | C25—C30—H30 | 119.3 |
C8—N1—N2—C9 | 160.9 (3) | C9—C10—C15—C14 | −176.5 (3) |
C23—N4—N5—C24 | −178.3 (3) | C16—O6—C17—C18 | −4.0 (5) |
C1—O2—C2—C7 | 10.6 (5) | C16—O6—C17—C22 | 176.3 (3) |
C1—O2—C2—C3 | −170.4 (4) | O6—C17—C18—C19 | 179.0 (3) |
O2—C2—C3—C4 | −178.5 (4) | C22—C17—C18—C19 | −1.3 (5) |
C7—C2—C3—C4 | 0.6 (6) | C17—C18—C19—C20 | 1.2 (5) |
C2—C3—C4—C5 | −0.4 (6) | C18—C19—C20—C21 | 0.3 (5) |
C3—C4—C5—C6 | −0.5 (6) | C18—C19—C20—C23 | 179.1 (3) |
C3—C4—C5—C8 | −178.2 (3) | C19—C20—C21—C22 | −1.8 (5) |
C4—C5—C6—C7 | 1.3 (5) | C23—C20—C21—C22 | 179.4 (3) |
C8—C5—C6—C7 | 179.1 (3) | C20—C21—C22—C17 | 1.8 (5) |
O2—C2—C7—C6 | 179.1 (3) | O6—C17—C22—C21 | 179.6 (3) |
C3—C2—C7—C6 | 0.2 (6) | C18—C17—C22—C21 | −0.1 (5) |
C5—C6—C7—C2 | −1.1 (6) | N5—N4—C23—O5 | 4.7 (5) |
N2—N1—C8—O1 | −2.8 (5) | N5—N4—C23—C20 | −175.6 (2) |
N2—N1—C8—C5 | 178.0 (3) | C19—C20—C23—O5 | −145.3 (3) |
C6—C5—C8—O1 | −28.7 (5) | C21—C20—C23—O5 | 33.4 (5) |
C4—C5—C8—O1 | 149.0 (4) | C19—C20—C23—N4 | 35.0 (4) |
C6—C5—C8—N1 | 150.6 (3) | C21—C20—C23—N4 | −146.3 (3) |
C4—C5—C8—N1 | −31.8 (5) | N4—N5—C24—C25 | 176.6 (3) |
N1—N2—C9—C10 | 175.0 (3) | N5—C24—C25—C30 | −36.5 (4) |
N2—C9—C10—C15 | −35.7 (5) | N5—C24—C25—C26 | 146.2 (3) |
N2—C9—C10—C11 | 148.7 (3) | C30—C25—C26—C27 | −2.3 (4) |
C15—C10—C11—C12 | −1.1 (5) | C24—C25—C26—C27 | 175.0 (3) |
C9—C10—C11—C12 | 174.7 (3) | C30—C25—C26—N6 | 175.1 (3) |
C15—C10—C11—N3 | 176.4 (3) | C24—C25—C26—N6 | −7.6 (5) |
C9—C10—C11—N3 | −7.8 (5) | O8—N6—C26—C25 | −15.4 (5) |
O4—N3—C11—C12 | 159.0 (3) | O7—N6—C26—C25 | 167.8 (3) |
O3—N3—C11—C12 | −19.7 (4) | O8—N6—C26—C27 | 162.2 (3) |
O4—N3—C11—C10 | −18.7 (5) | O7—N6—C26—C27 | −14.6 (4) |
O3—N3—C11—C10 | 162.7 (3) | C25—C26—C27—C28 | 1.9 (5) |
C10—C11—C12—C13 | 1.6 (5) | N6—C26—C27—C28 | −175.7 (3) |
N3—C11—C12—C13 | −176.0 (3) | C26—C27—C28—C29 | 0.6 (5) |
C11—C12—C13—C14 | −0.5 (6) | C27—C28—C29—C30 | −2.5 (6) |
C12—C13—C14—C15 | −0.9 (6) | C28—C29—C30—C25 | 2.0 (6) |
C13—C14—C15—C10 | 1.5 (6) | C26—C25—C30—C29 | 0.4 (5) |
C11—C10—C15—C14 | −0.5 (5) | C24—C25—C30—C29 | −177.1 (3) |
D—H···A | D—H | H···A | D···A | D—H···A |
N1—H1···O1i | 0.86 | 1.99 | 2.769 (3) | 150 |
N4—H4···O5i | 0.86 | 2.01 | 2.819 (3) | 156 |
Symmetry code: (i) x, y−1, z. |
Experimental details
Crystal data | |
Chemical formula | C15H13N3O4 |
Mr | 299.28 |
Crystal system, space group | Orthorhombic, Pca21 |
Temperature (K) | 273 |
a, b, c (Å) | 27.3272 (15), 4.8389 (3), 21.6639 (12) |
V (Å3) | 2864.7 (3) |
Z | 8 |
Radiation type | Mo Kα |
µ (mm−1) | 0.10 |
Crystal size (mm) | 0.35 × 0.23 × 0.13 |
Data collection | |
Diffractometer | Bruker APEX II CCD |
Absorption correction | Multi-scan (SADABS; Sheldrick, 2003) |
Tmin, Tmax | 0.966, 0.983 |
No. of measured, independent and observed [I > 2σ(I)] reflections | 24492, 2598, 2106 |
Rint | 0.055 |
(sin θ/λ)max (Å−1) | 0.595 |
Refinement | |
R[F2 > 2σ(F2)], wR(F2), S | 0.037, 0.094, 1.08 |
No. of reflections | 2598 |
No. of parameters | 400 |
No. of restraints | 1 |
H-atom treatment | H-atom parameters constrained |
Δρmax, Δρmin (e Å−3) | 0.15, −0.11 |
Computer programs: APEX2 (Bruker, 2005), SAINT (Bruker, 2005), SHELXS97 (Sheldrick, 1997a), SHELXL97 (Sheldrick, 1997a), SHELXTL (Sheldrick, 1997b).
D—H···A | D—H | H···A | D···A | D—H···A |
N1—H1···O1i | 0.86 | 1.99 | 2.769 (3) | 150.1 |
N4—H4···O5i | 0.86 | 2.01 | 2.819 (3) | 155.9 |
Symmetry code: (i) x, y−1, z. |
The chemistry of aroylhydrazones continues to attract much attention due to their coordination ability to metal ions (Singh et al., 1982; Salem, 1998) and their biological activity (Singh et al., 1982; Carcelli et al., 1995). As an extension of the work on the structural characterization of aroylhydrazone derivatives, the title compound, (I),was synthesized and its crystal structure is reported here.
There are two crystallographically independent molecules in the asymmetric unit (Fig. 1). The conformations of the two molecules are almost the same. Both display trans conformation with respect to the C9=N2 and C24=N5 double bond. The benzene rings of the two molecules, C2—C7(A), C10—C15(B), C17—C22(C) and C25—C30(D), make dihedral angles of 86.75 (9)° (A;B), but 8.3 (2)°(C;D)·The crystal structure is stabilized by intermolecular N—H···O hydrogen bonds, which yield chains running along b. (Table 1. and Fig. 2).