Use of a shared-memory parallel processor in the restrained least-squares procedure of Hendrickson and Konnert

The restrained least-squares refinement procedure PROLSQ of Hendrickson & Konnert [Hendrickson (1985). Methods in Enzymology, Vol. 115, edited by H.W. Wyckoff, C. H.W. Hirs & S.N. Timasheff, pp. 252-270. Orlando: Academic Press] has been implemented on a 30-processor Sequent Balance 21000 shared-memory parallel processor. The adaptation of PROLSQ to a general-purpose parallel computer offers the potential of performance increase as the physical limits are approached in traditional sequential and vector processing hardware.