Figure 4
Schematic representation of actin–myosin interaction in the contracting state and in rigor. In the contracting state, interaction between actin and myosin occurs in an incommensurate periodicities of both filaments and the myosin heads are cycling attachment to and detachment from actin in an asynchronous fashion. In the rigor state, all myosin heads from the thick filaments are tightly and stereospecifically bound to the actin filaments in accordance with the actin helical symmetry. |